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mRNAs for Vaccine Development
mRNAs for Vaccine Development

mRNAs for Vaccine Development

mRNA vaccines have been authorized for emergency use much less than one year after the emergence of COVID-19, demonstrating the extremely good improvement pace of the mRNA platform technology. However, even as the versatility of the mRNA platform could permit for the global development of latest vaccines, constraints which includes restrained intellectual property (IP), excessive price of goods, raw material bottlenecks, and shortage of skilled workforce restriction access to mRNA vaccines in low- and middle-earnings countries. Here, Seattle Genova presents a perspective on the global state of mRNA vaccine development for infectious diseases, and the manufacturing capabilities needed to enable vaccine access to fight ongoing/future pandemic and epidemic threats.

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Gene Name
Product Name
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Replicase polyprotein 1a (pp1a)
SARS-CoV-2 Replicase polyprotein 1a (pp1a) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-002
SARS-CoV-2 Replicase polyprotein 1a (pp1a) Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 Replicase polyprotein 1a (pp1a) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-002-LNP
SARS-CoV-2 Replicase polyprotein 1a (pp1a) Protein Circular RNA-LNP
VAC-RNA-002 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
S 2
SARS-CoV-2 S 2 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-003
SARS-CoV-2 S 2 Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 S 2 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-003-LNP
SARS-CoV-2 S 2 Protein Circular RNA-LNP
VAC-RNA-003 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
3a
SARS-CoV-2 3a Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-004
SARS-CoV-2 3a Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 3a Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-004-LNP
SARS-CoV-2 3a Protein Circular RNA-LNP
VAC-RNA-004 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
E 4
SARS-CoV-2 E 4 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-005
SARS-CoV-2 E 4 Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 E 4 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-005-LNP
SARS-CoV-2 E 4 Protein Circular RNA-LNP
VAC-RNA-005 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
M
SARS-CoV-2 M Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-006
SARS-CoV-2 M Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 M Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-006-LNP
SARS-CoV-2 M Protein Circular RNA-LNP
VAC-RNA-006 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
6
SARS-CoV-2 6 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-007
SARS-CoV-2 6 Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 6 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-007-LNP
SARS-CoV-2 6 Protein Circular RNA-LNP
VAC-RNA-007 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
7a
SARS-CoV-2 7a Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-008
SARS-CoV-2 7a Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 7a Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-008-LNP
SARS-CoV-2 7a Protein Circular RNA-LNP
VAC-RNA-008 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
8
SARS-CoV-2 8 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-009
SARS-CoV-2 8 Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 8 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-009-LNP
SARS-CoV-2 8 Protein Circular RNA-LNP
VAC-RNA-009 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
N
SARS-CoV-2 N Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-010
SARS-CoV-2 N Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 N Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-010-LNP
SARS-CoV-2 N Protein Circular RNA-LNP
VAC-RNA-010 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
rep 1a-1b
SARS-CoV-2 rep 1a-1b Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-011
SARS-CoV-2 rep 1a-1b Protein Circular RNA
In Vitro Transcribed mRNA template encoding SARS-CoV-2 rep 1a-1b Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-011-LNP
SARS-CoV-2 rep 1a-1b Protein Circular RNA-LNP
VAC-RNA-011 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
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