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SARS-CoV-2 7a Protein Circular RNA
VAC-RNA-008
SARS-CoV-2 7a Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:ORF7a protein (ORF7a) (Accessory protein 7a) (Protein U122) (Protein X4)
SKU:VAC-RNA-008-LNP
Product Name:SARS-CoV-2 7a Protein Circular RNA-LNP
Product Description:VAC-RNA-008 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-008
Product Name:SARS-CoV-2 7a Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding SARS-CoV-2 7a Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-008-LNP
Product Name:SARS-CoV-2 7a Protein Circular RNA-LNP
Product Description:VAC-RNA-008 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-008
Product Name:SARS-CoV-2 7a Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding SARS-CoV-2 7a Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A9
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.11
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P0DTC7

Gene Alias

ORF7a protein (ORF7a) (Accessory protein 7a) (Protein U122) (Protein X4)

Background

FUNCTION: Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 and sequestering it to perinuclear region, thereby preventing its antiviral function at cell membrane. {ECO:0000269|PubMed:33930332}.

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