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SARS-CoV-2 M Protein Circular RNA
VAC-RNA-006
SARS-CoV-2 M Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Membrane protein (M) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)
SKU:VAC-RNA-006-LNP
Product Name:SARS-CoV-2 M Protein Circular RNA-LNP
Product Description:VAC-RNA-006 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-006
Product Name:SARS-CoV-2 M Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding SARS-CoV-2 M Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-006-LNP
Product Name:SARS-CoV-2 M Protein Circular RNA-LNP
Product Description:VAC-RNA-006 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-006
Product Name:SARS-CoV-2 M Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding SARS-CoV-2 M Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A7
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.9
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P0DTC5

Gene Alias

Membrane protein (M) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)

Background

FUNCTION: Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins (By similarity). Regulates the localization of S protein at cis-Golgi, the place of virus budding (PubMed:33229438). May act by binding cytoplasmic c-terminus of S (PubMed:33229438). {ECO:0000255|HAMAP-Rule:MF_04202, ECO:0000255|PROSITE-ProRule:PRU01275, ECO:0000269|PubMed:33229438}.

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