Characterization of Liposomes by Differential Scanning Calorimetry (DSC)

Seattle Genova's expert researchers can offer clients with correct and brilliant DSC evaluation facts and offer statistics about the stability of proteins in biotherapeutics during process development. Protein stability analysis and studies can offer key data for the optimization of conditions for the development of biologics to boost up the pace of biotherapeutic drug development. We will offer you with a complete experimental operation plan and the very last evaluation report of protein stability consequences and different data evaluation reports. We are devoted to offering you with expert services on the stability of drug molecules in biotherapeutics that will help you clear up associated technical problems.

Differential Scanning Calorimetry (DSC) is a thermal analysis technique in which the heat flow into or out of a sample is measured as a function of temperature or time, while the sample is exposed to a controlled temperature program. DSC is a powerful analytical tool for characterizing the stability of proteins and other biomolecules directly in its native form with the aid of suitable thermodynamic models. This technique is very convenient requiring only minimal assay development, NO labeling or immobilization, and permits screening of large numbers of samples at low concentrations minimizing the consumption of valuable samples. It does this by measuring the heat change associated with the molecule’s thermal denaturation when heated at a constant rate. The resulting data provide critical guidance for biopharmaceutical development from protein engineering through pre-formulation and process development to formulation of the final product, driving productivity in biopharmaceutical research. We have reference samples meeting your requirement which are well-defined heat capacity over the range of temperatures to be scanned.

Deliverables

• A complete Differential Scanning Calorimetry service for physical characterization of liposomes.

• A complete work report.