With the wide list of products, Seattle Genova is successful in starting of mRNA therapeutic development services. Seattle Genova’s team has shown great results in production of custom mRNAs and its further services. We manufacture exceptional mRNA for a number of the maximum demanding applications in the enterprise today, providing custom-designed procedure improvement offerings primarily based on your particular mRNA and customer's application needs. Seattle Genova's GMP production of proteins has helped us construct one of the fastest-developing mRNA provider services in the industry.
Seattle Genova’s mRNA services
Seattle Genova provides more services along with custom mRNA production such as.
mRNA molecular design service
Seattle Genova provides the services of custom mRNA molecular designs according to the customer’s needs. It is synthesized through in vitro transcription of plasmid DNA with ORF (that encodes the target protein), and adding 5' cap and poly (A) in the end of the process. Seattle Genova ensures the stability and translational performance of mRNA by customization of synthetic factors including 5' cap and NTP.
Vector construction for IVT
Seattle Genova's advanced biotechnology platform has furnished hundreds of targeting vectors to clients worldwide. These targeting vectors had been efficaciously utilized in conventional and conditional knock-out, knock-in, and lots of different genetic amendment projects.
Plasmid production for mRNA synthesis
Seattle Genova's Plasmid DNA Preparation Service is accommodating to both small research labs in addition to large-scale manufacturing biotech and pharmaceutical companies, presenting you with excessive first-class plasmids with 100% full insert sequence accuracy. Choose from a number of our applications that will help you obtain tremendously efficient molecular transfection, and to guide your mRNA vaccine development, antibody production, and different preclinical research projects.
Plasmid linearization for mRNA production
Seattle Genova is trusted by customers for its years of experienced experts and has assisted several customers in offering linearized plasmids for mRNA applications. The production method starts with the generation of a plasmid DNA, to be in addition linearized to function as a template to transcribe the mRNA.
In vitro RNA transcription service
Seattle Genova has an in vitro transcription system designed for the constant manufacturing of massive quantities of high-specific-activity single-stranded capped or uncapped RNA in a brief quantity of time.
mRNA purification service
Seattle Genova offers custom production of HPLC mRNA columns and has a verified track record in groundbreaking messenger RNA purification and extraction processes. Generate high purity mRNA, freed from DNA and different RNA, for the improvement of novel drug and vaccine applicants for in vivo applications.
mRNA encapsulation service
Seattle Genova provides encapsulation of any charged molecules (e.g., mRNA, siRNA, shRNA, microRNA, plasmid DNA, protein) into either standard liposome formulations or a custom liposome formulation. Microfluidization (microfluidics), extrusion and sonication strategies are also provided to generate liposomes of a defined size.
Seattle Genova values costumer’s time and money that is why we provide high quality products in less time. Seattle Genova mRNA therapeutic development services have following features:
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