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mRNAs for Replacement Therapy Development
mRNAs for Replacement Therapy Development

mRNAs for Replacement Therapy Development

Protein replacement therapy has an extensive application in replacing missing or defective proteins with favorable proteins. mRNA-based therapeutics have turn out to be a brand new pillar for protein replacement therapy, which has been considerably explored in diverse fields, consisting of cardiac diseases, lung diseases, hematologic diseases, metabolic diseases, cancer, orthopedic diseases, neurogenic disorders, muscle atrophy, and so on. As a professional expertise in the discipline of mRNA therapeutics development, Seattle Genova provides a one-stop mRNA-based platform for our clients, to design and produce suitable mRNA products, to generate secure and powerful mRNA for replacement therapies, as well as to evaluate the features of mRNA-based therapies through using a panel of immunoassays.

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Alglucosidase alfa
Alglucosidase alfa In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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Product Description
SG-MRNA-LNP-1952-DCPS
Alglucosidase alfa In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Alglucosidase alfa ORF with Cap1 and 120nt PolyA tail.
Mecasermin
Mecasermin In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1953-DCPS
Mecasermin In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Mecasermin ORF with Cap1 and 120nt PolyA tail.
Galsulfase
Galsulfase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1954-DCPS
Galsulfase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Galsulfase ORF with Cap1 and 120nt PolyA tail.
Cocarboxylase
Cocarboxylase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1955-DCPS
Cocarboxylase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Cocarboxylase ORF with Cap1 and 120nt PolyA tail.
Alfimeprase
Alfimeprase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1957-DCPS
Alfimeprase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Alfimeprase ORF with Cap1 and 120nt PolyA tail.
Desmoteplase
Desmoteplase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1958-DCPS
Desmoteplase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Desmoteplase ORF with Cap1 and 120nt PolyA tail.
Ranpirnase
Ranpirnase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1959-DCPS
Ranpirnase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Ranpirnase ORF with Cap1 and 120nt PolyA tail.
Verpasep caltespen
Verpasep caltespen In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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Product Description
SG-MRNA-LNP-1960-DCPS
Verpasep caltespen In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Verpasep caltespen ORF with Cap1 and 120nt PolyA tail.
rhGAD65
rhGAD65 In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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SG-MRNA-LNP-1961-DCPS
rhGAD65 In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding rhGAD65 ORF with Cap1 and 120nt PolyA tail.
Praconase
Praconase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
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Product Description
SG-MRNA-LNP-1963-DCPS
Praconase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
In vitro transcribed mRNA encoding Praconase ORF with Cap1 and 120nt PolyA tail.
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