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mRNAs for Vaccine Development
mRNAs for Vaccine Development

mRNAs for Vaccine Development

mRNA vaccines have been authorized for emergency use much less than one year after the emergence of COVID-19, demonstrating the extremely good improvement pace of the mRNA platform technology. However, even as the versatility of the mRNA platform could permit for the global development of latest vaccines, constraints which includes restrained intellectual property (IP), excessive price of goods, raw material bottlenecks, and shortage of skilled workforce restriction access to mRNA vaccines in low- and middle-earnings countries. Here, Seattle Genova presents a perspective on the global state of mRNA vaccine development for infectious diseases, and the manufacturing capabilities needed to enable vaccine access to fight ongoing/future pandemic and epidemic threats.

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Capsid protein VP0 (VP4-VP2)
HHAV (isolate LA) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-102
HHAV (isolate LA) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV (isolate LA) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-102-LNP
HHAV (isolate LA) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-102 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV (isolate CR326) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-103
HHAV (isolate CR326) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV (isolate CR326) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-103-LNP
HHAV (isolate CR326) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-103 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV genotype IB (isolate HM175) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-104
HHAV genotype IB (isolate HM175) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV genotype IB (isolate HM175) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-104-LNP
HHAV genotype IB (isolate HM175) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-104 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV genotype IB (isolate MBB) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-105
HHAV genotype IB (isolate MBB) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV genotype IB (isolate MBB) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-105-LNP
HHAV genotype IB (isolate MBB) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-105 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV (isolate HAS-15) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-106
HHAV (isolate HAS-15) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV (isolate HAS-15) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-106-LNP
HHAV (isolate HAS-15) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-106 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV genotype IIA (isolate CF-53) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-107
HHAV genotype IIA (isolate CF-53) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV genotype IIA (isolate CF-53) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-107-LNP
HHAV genotype IIA (isolate CF-53) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-107 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV (isolate GBM) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-108
HHAV (isolate GBM) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV (isolate GBM) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-108-LNP
HHAV (isolate GBM) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-108 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV genotype IIB (isolate SLF88) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-109
HHAV genotype IIB (isolate SLF88) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV genotype IIB (isolate SLF88) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-109-LNP
HHAV genotype IIB (isolate SLF88) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-109 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV genotype IIIA (isolate NOR-21) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-110
HHAV genotype IIIA (isolate NOR-21) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV genotype IIIA (isolate NOR-21) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-110-LNP
HHAV genotype IIIA (isolate NOR-21) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-110 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein VP0 (VP4-VP2)
HHAV genotype IIIA (isolate GA76) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-111
HHAV genotype IIIA (isolate GA76) Capsid protein VP0 (VP4-VP2) Protein Circular RNA
In Vitro Transcribed mRNA template encoding HHAV genotype IIIA (isolate GA76) Capsid protein VP0 (VP4-VP2) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-111-LNP
HHAV genotype IIIA (isolate GA76) Capsid protein VP0 (VP4-VP2) Protein Circular RNA-LNP
VAC-RNA-111 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
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