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mRNAs for Vaccine Development
mRNAs for Vaccine Development

mRNAs for Vaccine Development

mRNA vaccines have been authorized for emergency use much less than one year after the emergence of COVID-19, demonstrating the extremely good improvement pace of the mRNA platform technology. However, even as the versatility of the mRNA platform could permit for the global development of latest vaccines, constraints which includes restrained intellectual property (IP), excessive price of goods, raw material bottlenecks, and shortage of skilled workforce restriction access to mRNA vaccines in low- and middle-earnings countries. Here, Seattle Genova presents a perspective on the global state of mRNA vaccine development for infectious diseases, and the manufacturing capabilities needed to enable vaccine access to fight ongoing/future pandemic and epidemic threats.

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COI
Anthrax sp. SLB-2003 COI Protein Circular RNA
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Product Description
VAC-RNA-042
Anthrax sp. SLB-2003 COI Protein Circular RNA
In Vitro Transcribed mRNA template encoding Anthrax sp. SLB-2003 COI Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-042-LNP
Anthrax sp. SLB-2003 COI Protein Circular RNA-LNP
VAC-RNA-042 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
NADH1
Anthrax proconcisus NADH1 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-043
Anthrax proconcisus NADH1 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Anthrax proconcisus NADH1 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-043-LNP
Anthrax proconcisus NADH1 Protein Circular RNA-LNP
VAC-RNA-043 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
NADH1
Anthrax maculatus NADH1 Protein Circular RNA
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Product_name
Product Description
VAC-RNA-044
Anthrax maculatus NADH1 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Anthrax maculatus NADH1 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-044-LNP
Anthrax maculatus NADH1 Protein Circular RNA-LNP
VAC-RNA-044 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
rstA
Vibrio cholerae 569B rstA Protein Circular RNA
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Product_name
Product Description
VAC-RNA-045
Vibrio cholerae 569B rstA Protein Circular RNA
In Vitro Transcribed mRNA template encoding Vibrio cholerae 569B rstA Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-045-LNP
Vibrio cholerae 569B rstA Protein Circular RNA-LNP
VAC-RNA-045 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
rstB
Vibrio cholerae 569B rstB Protein Circular RNA
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Product_name
Product Description
VAC-RNA-046
Vibrio cholerae 569B rstB Protein Circular RNA
In Vitro Transcribed mRNA template encoding Vibrio cholerae 569B rstB Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-046-LNP
Vibrio cholerae 569B rstB Protein Circular RNA-LNP
VAC-RNA-046 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (strain Jamaica/1409/1983) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-047
DENV-2 (strain Jamaica/1409/1983) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Jamaica/1409/1983) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-047-LNP
DENV-2 (strain Jamaica/1409/1983) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-047 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-4(strain Dominica/814669/1981) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-048
DENV-4(strain Dominica/814669/1981) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-4(strain Dominica/814669/1981) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-048-LNP
DENV-4(strain Dominica/814669/1981) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-048 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (strain Puerto Rico/PR159-S1/1969) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-049
DENV-2 (strain Puerto Rico/PR159-S1/1969) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Puerto Rico/PR159-S1/1969) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-049-LNP
DENV-2 (strain Puerto Rico/PR159-S1/1969) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-049 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (isolate Thailand/0168/1979) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-050
DENV-2 (isolate Thailand/0168/1979) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (isolate Thailand/0168/1979) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-050-LNP
DENV-2 (isolate Thailand/0168/1979) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-050 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (strain Thailand/NGS-C/1944) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-051
DENV-2 (strain Thailand/NGS-C/1944) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Thailand/NGS-C/1944) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-051-LNP
DENV-2 (strain Thailand/NGS-C/1944) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-051 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
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