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mRNAs for Vaccine Development
mRNAs for Vaccine Development

mRNAs for Vaccine Development

mRNA vaccines have been authorized for emergency use much less than one year after the emergence of COVID-19, demonstrating the extremely good improvement pace of the mRNA platform technology. However, even as the versatility of the mRNA platform could permit for the global development of latest vaccines, constraints which includes restrained intellectual property (IP), excessive price of goods, raw material bottlenecks, and shortage of skilled workforce restriction access to mRNA vaccines in low- and middle-earnings countries. Here, Seattle Genova presents a perspective on the global state of mRNA vaccine development for infectious diseases, and the manufacturing capabilities needed to enable vaccine access to fight ongoing/future pandemic and epidemic threats.

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Capsid protein C (Capsid protein)
DENV-1 (strain Nauru/West Pac/1974) (DENV-1) Capsid protein C (Capsid protein) Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-052
DENV-1 (strain Nauru/West Pac/1974) (DENV-1) Capsid protein C (Capsid protein) Protein Circular RNA
In Vitro Transcribed mRNA template encoding DENV-1 (strain Nauru/West Pac/1974) (DENV-1) Capsid protein C (Capsid protein) Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-052-LNP
DENV-1 (strain Nauru/West Pac/1974) (DENV-1) Capsid protein C (Capsid protein) Protein Circular RNA-LNP
VAC-RNA-052 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Protein prM
DENV-2 (strain Thailand/PUO-218/1980) Protein prM Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-053
DENV-2 (strain Thailand/PUO-218/1980) Protein prM Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Thailand/PUO-218/1980) Protein prM Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-053-LNP
DENV-2 (strain Thailand/PUO-218/1980) Protein prM Circular RNA-LNP
VAC-RNA-053 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Protein C (Core protein)
DENV-1 (strain Brazil/97-11/1997) (DENV-1) Protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-054
DENV-1 (strain Brazil/97-11/1997) (DENV-1) Protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-1 (strain Brazil/97-11/1997) (DENV-1) Protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-054-LNP
DENV-1 (strain Brazil/97-11/1997) (DENV-1) Protein C (Core protein) Circular RNA-LNP
VAC-RNA-054 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-1 (strain Thailand/AHF 82-80/1980) (DENV-1) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-055
DENV-1 (strain Thailand/AHF 82-80/1980) (DENV-1) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-1 (strain Thailand/AHF 82-80/1980) (DENV-1) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-055-LNP
DENV-1 (strain Thailand/AHF 82-80/1980) (DENV-1) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-055 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-1 (strain Jamaica/CV1636/1977) (DENV-1) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-056
DENV-1 (strain Jamaica/CV1636/1977) (DENV-1) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-1 (strain Jamaica/CV1636/1977) (DENV-1) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-056-LNP
DENV-1 (strain Jamaica/CV1636/1977) (DENV-1) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-056 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Envelope protein E
DENV-2 (strain Tonga/EKB194/1974) Envelope protein E Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-057
DENV-2 (strain Tonga/EKB194/1974) Envelope protein E Protein Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Tonga/EKB194/1974) Envelope protein E Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-057-LNP
DENV-2 (strain Tonga/EKB194/1974) Envelope protein E Protein Circular RNA-LNP
VAC-RNA-057 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-3 (strain Philippines/H87/1956) (DENV-3) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-058
DENV-3 (strain Philippines/H87/1956) (DENV-3) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-3 (strain Philippines/H87/1956) (DENV-3) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-058-LNP
DENV-3 (strain Philippines/H87/1956) (DENV-3) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-058 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (strain Thailand/16681/1984) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-059
DENV-2 (strain Thailand/16681/1984) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Thailand/16681/1984) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-059-LNP
DENV-2 (strain Thailand/16681/1984) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-059 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (strain 16681-PDK53) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-060
DENV-2 (strain 16681-PDK53) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain 16681-PDK53) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-060-LNP
DENV-2 (strain 16681-PDK53) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-060 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Capsid protein C (Core protein)
DENV-2 (strain China/D2-04) Capsid protein C (Core protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-061
DENV-2 (strain China/D2-04) Capsid protein C (Core protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain China/D2-04) Capsid protein C (Core protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-061-LNP
DENV-2 (strain China/D2-04) Capsid protein C (Core protein) Circular RNA-LNP
VAC-RNA-061 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
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