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Aed a 1 Circular RNA
Aed a 1 Circular RNA
ALG-ORNA-0021
Aed a 1 Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Apyrase
SKU:ALG-ORNA-0021-LNP
Product Name:Aed a 1 Circular RNA-LNP
Product Description:ALG-ORNA-0021 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0021
Product Name:Aed a 1 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Aed a 1 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:ALG-ORNA-0021-LNP
Product Name:Aed a 1 Circular RNA-LNP
Product Description:ALG-ORNA-0021 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0021
Product Name:Aed a 1 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Aed a 1 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
Aed a 1
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.25
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Allergy Tolerization
Background

Gene Alias

Apyrase

Background

Allergenicity reference:PubMed:11717185 Route of allergen exposure:Injection; - rAed a 1 bound to human IgE, as detected by ELISA, Nine out of 31 (29%) of the subjects with positive immediate bite tests also had a positive rAed a 1 immediate skin reaction. Six of 33 (18%) of the subjects with positive delayed bite tests also had a positive rAed a 1 delayed skin reaction. - 43% of 28 mosquito bite test-positive subjects had a positive skin test to rAed a 1: medline 21203342

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