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Aed a 12 Circular RNA
Aed a 12 Circular RNA
ALG-ORNA-0024
Aed a 12 Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Triosphosphate isomerase
SKU:ALG-ORNA-0024-LNP
Product Name:Aed a 12 Circular RNA-LNP
Product Description:ALG-ORNA-0024 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0024
Product Name:Aed a 12 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Aed a 12 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:ALG-ORNA-0024-LNP
Product Name:Aed a 12 Circular RNA-LNP
Product Description:ALG-ORNA-0024 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0024
Product Name:Aed a 12 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Aed a 12 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
Aed a 12
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.28
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Allergy Tolerization
Background

Gene Alias

Triosphosphate isomerase

Background

Route of allergen exposure:Injection; Seven of 19 subjects with allergy and rhinitis to house dust mite and/or cockroach or shrimp were tested for by SPT to whole body extract of Aedes aegypti mosquito. When their sera were tested by ELISA to recombinant protein, with the seven having positive IgE binding by ELISA out of the 19. Five negative controls did not have binding to this ELISA. This data suggests IgE sensitization and possible allergy. Exposure may be by injection or may be by inhalation

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