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Aln g 4 Circular RNA
Aln g 4 Circular RNA
ALG-ORNA-0038
Aln g 4 Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Polcalcin
SKU:ALG-ORNA-0038-LNP
Product Name:Aln g 4 Circular RNA-LNP
Product Description:ALG-ORNA-0038 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0038
Product Name:Aln g 4 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Aln g 4 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:ALG-ORNA-0038-LNP
Product Name:Aln g 4 Circular RNA-LNP
Product Description:ALG-ORNA-0038 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0038
Product Name:Aln g 4 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Aln g 4 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
Aln g 4
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.42
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Allergy Tolerization
Background

Gene Alias

Polcalcin

Background

Allergenicity reference:PubMed:9862740 Route of allergen exposure:Airway; - rAln g 4 reacted with serum IgE from 18% of pollen-allergic patients tested(n = 122). Patients were allergic to: olive (n = 50), grass (n = 20), birch (n = 12), mugwort pollen (n = 20), and maize (n = 20). - Purified rAln g 4 elicited dose-dependent basophil histamine release in 3 patients tested and immediate type skin reactions in 3 patients tested.

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