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Amb a 5 Circular RNA
Amb a 5 Circular RNA
ALG-ORNA-0060
Amb a 5 Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
SKU:ALG-ORNA-0060-LNP
Product Name:Amb a 5 Circular RNA-LNP
Product Description:ALG-ORNA-0060 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0060
Product Name:Amb a 5 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Amb a 5 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:ALG-ORNA-0060-LNP
Product Name:Amb a 5 Circular RNA-LNP
Product Description:ALG-ORNA-0060 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0060
Product Name:Amb a 5 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Amb a 5 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
Amb a 5
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.64
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Allergy Tolerization
Background

Background

Allergenicity reference:PubMed:7685794‚PubMed:1390654 Route of allergen exposure:Airway; 18 selected ragweed-allergic patients showed serum IgE binding to native and rAmb a 5 in DARIA; histamine release from basophils from 2 allergic patients induced by both native and rAmb a 5 - 17% of 65 pateints with ragweed hay fever showed IgE binding to Amb a 5 in RAST.

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