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Ana c 1 Circular RNA
Ana c 1 Circular RNA
ALG-ORNA-0069
Ana c 1 Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Profilin
SKU:ALG-ORNA-0069-LNP
Product Name:Ana c 1 Circular RNA-LNP
Product Description:ALG-ORNA-0069 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0069
Product Name:Ana c 1 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Ana c 1 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:ALG-ORNA-0069-LNP
Product Name:Ana c 1 Circular RNA-LNP
Product Description:ALG-ORNA-0069 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:ALG-ORNA-0069
Product Name:Ana c 1 Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Ana c 1 was further circularized with Seattle Genova's Ostar technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
Ana c 1
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.73
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Allergy Tolerization
Background

Gene Alias

Profilin

Background

Allergenicity reference:PubMed:12065910 Route of allergen exposure:Food; 8 out of 19 sera (42%) from pineapple-sensitive patients showed IgE binding to recombinant Ana c 1 on immunoblot. IgE binding to pineapple extract (1 patient tested) was strongly inhibited by pineapple profilin (about 80%).

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