Gene Alias

Lysosomal aspartic protease

Background

Allergenicity reference:PubMed:28235135 Route of allergen exposure:Injection; Allergenicity:15 subjects with airway and/or dermal allergic reactions upon exposure to mosquito bites or Case history of mosquito allergy (bites and/or inhalation of insect parts) from subjects living in the Caribbean island of Martinique with asthma and/or rhinitis and specific IgE to mosquito extract. Proteins of defatted, freeze dried mosquitoes, with proteins separated on 2D gels and immunoblotted with six individual sera Abstract presented at EAACI Barcelona, 2015. IgE binding spots were identified by mass LC/MS-MS of trypsinized gel spots. Lysosomal aspartic protease bound IgE from 3 of 6 subjects.