Gene Accession
Q9UM73
Gene Alias
Protein names Recommended name ALK tyrosine kinase receptor Curated EC number EC:2.7.10.1 2 Publications (UniProtKB | ENZYME | Rhea) Alternative names Anaplastic lymphoma kinase 1 Publication CD Antigen Name CD246 Gene names Name ALK
Background
ALK Fusion is present in 0.53% of AACR GENIE cases, with lung adenocarcinoma, non-small cell lung carcinoma, inflammatory myofibroblastic tumor, pancreatic adenocarcinoma, and adenocarcinoma of unknown primary having the greatest prevalence. Genomic fusions of the anaplastic lymphoma kinase gene (ALK) are a well‐established therapy target in non‐small cell lung cancer (NSCLC).