Gene Accession
P29274
Gene Alias
Protein names Recommended name Adenosine receptor A2a Gene names Name ADORA2A Synonyms ADORA2
Background
Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain. AR plays pivotal roles in prostate cancer, especially castration-resistant prostate cancer (CRPC). AR Amplification is present in 0.66% of AACR GENIE cases, with prostate adenocarcinoma, breast invasive ductal carcinoma, invasive breast carcinoma, lung adenocarcinoma, and invasive breast carcinoma, NOS having the greatest prevalence.