Gene Accession
P29277
Gene Alias
Protein names Recommended name Adenosine receptor A2a Gene names Name ADORA2A Synonyms ADORA5
Background
T878A is frequent in abiraterone-treated CRPC patients producing a progesterone-activated AR mutant protein leading to abiraterone-resistance. Resistance has been observed for the following drugs in samples curated with this mutation, Abiraterone, Androgen, Enzalutamide, Flutamide, Ketoconazole, LHRH.