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BioActive Human AR (W741,T878A) Recombinant Protein,Fc Tag
SGRP00651
BioActive Human AR (W741,T878A) Recombinant Protein,Fc Tag
Source:Full length Human AR (L702H,T878A), expressed in HEK293 cells.
SKU:SGRP00651-100UG
Product Name:BioActive Human AR (W741,T878A) Recombinant Protein,Fc Tag
Product Description:Human AR with mutation W741,T878A expressed in HEK293 cells with activity confimed by ELISA.
SKU:SGRP00651-100UG
Product Name:BioActive Human AR (W741,T878A) Recombinant Protein,Fc Tag
Product Description:Human AR with mutation W741,T878A expressed in HEK293 cells with activity confimed by ELISA.
PROPERTIES
Biological Activity:
Fully biologically active
Purity:
> 95% by SDS-PAGE & HPLC
Endotoxin Level:
< 1.0 EU per μg protein as determined by the LAL method
Expression System:
HEK293 Cells
Format:
Recombinant
Species:
Human
Applications:
Sandwich ELISA Functional Studies Mass Spectrometry SDS-PAGE HPLC
Form:
Lyophilized from sterile PBS, pH 7.34
Concentration:
N/A
Stability and Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:
Reconstitute with Phosphate Buffered Saline.
Related Categories
BioActive Biomarker Proteins
Background

Gene Accession

P29277

Gene Alias

Protein names Recommended name Adenosine receptor A2a Gene names Name ADORA2A Synonyms ADORA5

Background

T878A is frequent in abiraterone-treated CRPC patients producing a progesterone-activated AR mutant protein leading to abiraterone-resistance. Resistance has been observed for the following drugs in samples curated with this mutation, Abiraterone, Androgen, Enzalutamide, Flutamide, Ketoconazole, LHRH.

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