Gene Accession
Q13315
Gene Alias
Protein names Recommended name Serine-protein kinase ATM EC number EC:2.7.11.1 6 Publications (UniProtKB | ENZYME | Rhea) Alternative names Ataxia telangiectasia mutated (A-T mutated) Gene names Name ATM
Background
The ATM gene is located within the minimally deleted region on chromosome 11q. Deletions of chromosome 11q are associated with a severe clinical phenotype and reduced survival in CLL. The relationship between ATM mutations and 11q deletions in the pathogenesis of CLL has not been fully resolved.