Gene Accession
P15056
Gene Alias
Protein names Recommended name Serine/threonine-protein kinase B-raf Curated EC number EC:2.7.11.1 2 Publications (UniProtKB | ENZYME | Rhea) Alternative names Proto-oncogene B-Raf p94 v-Raf murine sarcoma viral oncogene homolog B1 Gene names Name BRAF Imported Synonyms BRAF1, RAFB1
Background
The BRAF V600E mutation constitutes more than 80% of BRAF mutations. Other BRAF mutations include V600K (1798 1799 GT > AA; 5% to 6%; valine to lysine), V600R (1798 1799 GT > AG; 1%; valine to arginine), V600E2 (1799 1800 AG > AA; 0.7%) and V600D (1799 1800 AG > AT).