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Gene Accession
P38398
Gene Alias
Protein names Recommended name Breast cancer type 1 susceptibility protein EC number EC:2.3.2.27 6 Publications (UniProtKB | ENZYME | Rhea) Alternative names RING finger protein 53 RING-type E3 ubiquitin transferase BRCA1 Curated Gene names Name BRCA1 Synonyms RNF53
Background
The BRCA1 protein is involved in repairing damaged DNA. In the nucleus of many types of normal cells, the BRCA1 protein interacts with several other proteins to mend breaks in DNA. These breaks can be caused by natural and medical radiation or other environmental exposures, and they also occur when chromosomes exchange genetic material in preparation for cell division. By helping to repair DNA, the BRCA1 protein plays a critical role in maintaining the stability of a cell's genetic information.
