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HAdV-4 E1B protein Protein Circular RNA
VAC-RNA-024
HAdV-4 E1B protein Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:E1B protein, small T-antigen (E1B 19 kDa protein) (E1B-19K)
SKU:VAC-RNA-024-LNP
Product Name:HAdV-4 E1B protein Protein Circular RNA-LNP
Product Description:VAC-RNA-024 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-024
Product Name:HAdV-4 E1B protein Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding HAdV-4 E1B protein Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-024-LNP
Product Name:HAdV-4 E1B protein Protein Circular RNA-LNP
Product Description:VAC-RNA-024 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-024
Product Name:HAdV-4 E1B protein Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding HAdV-4 E1B protein Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A25
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.27
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P10406

Gene Alias

E1B protein, small T-antigen (E1B 19 kDa protein) (E1B-19K)

Background

FUNCTION: Putative adenovirus Bcl-2 homolog that inhibits apoptosis induced by TNF or FAS pathways, as well as p53-mediated apoptosis. Without E1B 19K function, virus production is compromised because of premature death of host cell. Interacts with Bax protein in cell lysates (By similarity). {ECO:0000250}.

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