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HAdV-4 L5 Protein Circular RNA
VAC-RNA-025
HAdV-4 L5 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Fiber protein (SPIKE) (Protein IV)
SKU:VAC-RNA-025-LNP
Product Name:HAdV-4 L5 Protein Circular RNA-LNP
Product Description:VAC-RNA-025 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-025
Product Name:HAdV-4 L5 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding HAdV-4 L5 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-025-LNP
Product Name:HAdV-4 L5 Protein Circular RNA-LNP
Product Description:VAC-RNA-025 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-025
Product Name:HAdV-4 L5 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding HAdV-4 L5 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A26
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.28
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P36844

Gene Alias

Fiber protein (SPIKE) (Protein IV)

Background

FUNCTION: Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CXCAR to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity). {ECO:0000250}.

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