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HAdV-4 POL Protein Circular RNA
VAC-RNA-022
HAdV-4 POL Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:DNA polymerase (EC 2.7.7.7)
SKU:VAC-RNA-022-LNP
Product Name:HAdV-4 POL Protein Circular RNA-LNP
Product Description:VAC-RNA-022 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-022
Product Name:HAdV-4 POL Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding HAdV-4 POL Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-022-LNP
Product Name:HAdV-4 POL Protein Circular RNA-LNP
Product Description:VAC-RNA-022 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-022
Product Name:HAdV-4 POL Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding HAdV-4 POL Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A23
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.25
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P87503

Gene Alias

DNA polymerase (EC 2.7.7.7)

Background

FUNCTION: Eukaryotic-type DNA polymerase involved in viral genomic replication. DNA synthesis is protein primed, and acts in a strand displacement replication. Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication. The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis. {ECO:0000250|UniProtKB:P03261, ECO:0000250|UniProtKB:P04495, ECO:0000255|HAMAP-Rule:MF_04055}.

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