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Lactase  In Vitro Transcribed mRNA-LNP
SG-MRNA-LNP-1909
Lactase In Vitro Transcribed mRNA-LNP
Source:The ORF of Lactase was cloned in our IVT vector and mRNA was prepared through in vitro transcription and purification. The purified mRNA was further encapsulated with LNP(DSPC:Cholesterol:DMG-PEG:SM102).
Alternative Names:Lactase
SKU:SG-MRNA-LNP-1909-DCPS
Product Name:Lactase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
Product Description:Lactase In Vitro Transcribed mRNA encapsulated with LNP(DSPC:Cholesterol:DMG-PEG:SM102)
SKU:SG-MRNA-LNP-1909-DCPS
Product Name:Lactase In Vitro Transcribed mRNA-LNP(DSPC:Cholesterol:DMG-PEG:SM102)
Product Description:Lactase In Vitro Transcribed mRNA encapsulated with LNP(DSPC:Cholesterol:DMG-PEG:SM102)
PROPERTIES
Cap:
m7GpppN
5'-UTR:
5' -untranslated region derived from human alpha-globin RNA with an optimized Kozak sequence
ORF:
Lactase
3'-UTR:
3' UTR comprising two sequence elements derived from the aminoterminal enhancer of split (AES) mRNA and the mitochondrial encoded 12S ribosomal RNA
Poly(A) Tail:
A 110-nucleotide poly(A)-tail consisting of a stretch of 30 adenosine residues, followed by a 10-nucleotide linker sequence and another 70 adenosine residues.
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-20 °C
Buffer:
PBS, pH7.4
Cryoprotectant:
Trehalose
Background

Gene Alias

Lactase

Background

Tilactase is a beta-D-galactosidase obtained from Aspergillus oryzae. Lactose is the primary disaccharide found in dairy products. Tilactase is a type of lactase which is the enzyme that is in charge of the breakdown of lactose to glucose and galactose which can be used by the body. Basically, tilactase acts by replacing the missing lactase in the body and allows avoidance of the reach of lactose to the small intestine and the normal bacteria and thus, preventing the symptoms of the lactose intolerance. Once tilactase has metabolized the lactose, the metabolism products are reabsorbed by the normal process of digestion.

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