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SARS-CoV-2 ORF3b Protein Circular RNA
VAC-RNA-016
SARS-CoV-2 ORF3b Protein Circular RNA
Source：In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names：Putative ORF3b protein (ORF3b)
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SKU：VAC-RNA-016-LNP
Product Name：SARS-CoV-2 ORF3b Protein Circular RNA-LNP
Product Description：VAC-RNA-016 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU：VAC-RNA-016
Product Name：SARS-CoV-2 ORF3b Protein Circular RNA
Product Description：In Vitro Transcribed mRNA template encoding SARS-CoV-2 ORF3b Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU：VAC-RNA-016-LNP
Product Name：SARS-CoV-2 ORF3b Protein Circular RNA-LNP
Product Description：VAC-RNA-016 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU：VAC-RNA-016
Product Name：SARS-CoV-2 ORF3b Protein Circular RNA
Product Description：In Vitro Transcribed mRNA template encoding SARS-CoV-2 ORF3b Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A17
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.19
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P0DTF1

Gene Alias

Putative ORF3b protein (ORF3b)

Background

FUNCTION: Acts as an interferon antagonist when expressed ex vivo. {ECO:0000269|PubMed:32941788}.

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