Products
Products
Services
Applications
Molecular Cloning
Cell Culture By Cell Type
Immunohistochemistry
Hematology
Food & Beverage Testing
Advanced Gene Editing
Cancer Research
Cell & Developmental Biology Research
Cell Signaling
Immunology Research
Metabolomics Research
Neuroscience Research
Pharmacology & Drug Discovery Research
Glycobiology
Products
BioActive Proteins
mRNA Products
Service
Molecular Cloning Services
Protein Interaction Testings
Virus Production Services
Antibody Production Services
In Vitro Transcribed mRNA Services
Stable Cell Line Construction Services
Protein Production Services
Biotesting Services
Organoid Services
LNPs for mRNA Delivery
Custom Protein Labeling Services
CRISPR/cas9 Therapeutics Development
Company
About Us
Contact Us
Press Releases
Products
Services
Company
BioActive Proteins
BioActive Biomarker Proteins
Proteins for Allergy Research
mRNA Products
mRNAs for Vaccine Development
mRNAs for Replacement Therapy Development
mRNAs for Allergy Tolerization
mRNAs for Stem Cell Differentiation
Circular RNAs
Reporter Gene mRNA
mRNAs for Cancer Vaccine Research
Molecular Cloning Services
Tissue DNA Extraction
Traditional Subcloning
Insertion Of Tags
Point Mutations
High Throughput Plasmid DNA Preparation
Reporter Addition/Removal Service
Antibiotic Switching Service
Plasmid DNA Production
Protein Interaction Testings
Biologics Affinity & Kinetic Characterization
Lipoparticle Binding Test
Protein-DNA/RNA Binding Test
Drug-protein Binding Test With SPR
Protein-peptides Binding Affinity & Kinetics Testing
Enzyme Kinetic Assays With SPR
Antibody Affinity And Kinetics Characrization
Biotherapeutic Drug Discovery With SPR
Lead Characterization Of High Affinity Biologic Interactions With SPR
Fc Receptor Binding Asaay
Serum Protein Binding (ADME)
Bioanalytics In Drug Development And QC
Virus Production Services
Lentivirus Production Services
Tet-off Lentivirus Production Service
Tet-On Lentivirus Production Service
Lentivirus Production For CART Therapy
Lentivirus Production For CRISPER-Cas9 Delivery
Lentivirus Production For Neuro Cell Transfection
Adenovirus Production Services
AAV Production Services
CNS Targeting AAV Production Services
Heart Targeting AAV Production Services
Kidney Targeting AAV Production Services
Liver Targeting AAV Production Service
Lung Targeting AAV Production Services
Pancreas Targeting AAV Production Services
Photoreceptor Cells Targeting AAV Production Services
RPE (Retinal Pigment Epithelium) Targeting AAV Production Services
Skeletal Muscle Targeting AAV Production Services
Antibody Production Services
SpeedeeTM Monoclonal Antibody Production
SpeedeeTM Molecular Biology Services
SpeedyTM Antigen Production Services
SpeedyTM Polyclonal Antibody Production
SpeedeeTM Rabbit Polyclonal Antibodies For Fruit Flies
SpeedeeTM Rabbit Polyclonal Antibodies For Zebrafish (Danio rerio)
SpeedeeTM Rabbit Polyclonal Antibodies For Arabidopsis
SpeedeeTM Rabbit Polyclonal Antibodies For Yeast
SpeedeeTM Rabbit Polyclonal Antibodies For E.coli
SpeedeeTM Rabbit Polyclonal Antibodies For Small Molecules
SpeedeeTM Anti-PTM Rabbit Polyclonal Antibody Development
SpeedeeTM Anti-scFv Rabbit Polyclonal Antibody Development
SpeedeeTM Anti-immunoglobulin CDR Polyclonal Antibody Development
Cynomolgus Monkey Cross-reactive Antibody Development Service
In Vitro Transcribed mRNA Services
Custom mRNA Synthesis
Self-amplifying RNA Production
Custom Circular RNA Production
mRNA Based Gene Editing Tools
mRNA Immunization
New Lipid Nanoparticle Formulation Development Service
mRNA Structural Modifications
mRNA-Based Replacement Therapy
mRNA Development for Cell Therapy
MRNA Based Vaccine Development
LNP Formulated RNA Production Service
mRNA Analysis and Characterization
mRNA Identity Analysis
Capping Efficiency and Poly(A) Tail Characterization
mRNA Purity and Impurities Analysis
In Vitro Transcribed RNA Expression Analysis
Potency Test of mRNA
Safety Evaluation of mRNA
Stability Assessment of mRNA
mRNA Drug Development Services
mRNA Molecular Design Service
Vector Construction For IVT
Plasmid Linearization For mRNA Production
Plasmid Production For mRNA Synthesis
In Vitro RNA Transcription Service
mRNA Purification Services
mRNA Encapsulation Service
mRNA Production With Cytidine-containing Tails That Enhance mRNA Stability
mRNA Formulation Services
Viral Vector Construction For mRNA Delivery
Lipid Based Particle Production For mRNA Delivery
Cationic Nanoemulsion Production For mRNA Delivery
Naked mRNA Vaccine Production
Non-viral Vector Construction For mRNA Delivery
Polymer Synthesis For Polymer-based Delivery Of mRNA
Dendritic Cells-Based mRNA Vaccine Production
Peptide Conjugated mRNA Production
Virus-Like Replicon Particle Production For mRNA Delivery
Co-delivery Of mRNA Vaccines
Lyophilization Of Lipid Nanoparticle-formulated mRNA
mRNA Electroporation Services
Polymer-lipid Hybrid Particle Production For mRNA Delivery
RNApatch Production For mRNA Delivery
mRNA Engineering For Improved Stability And Efficacy
5’UTR & 3’UTR Engineering For The Improvement Of Stability Of mRNA
ORF Optimization For Improved mRNA Stability And Efficacy
Modification of 5’Cap For The Improvement Of Stability Of mRNA
Engineering Of Poly-A Tail For The Improvement Of Stability Of mRNA
mRNA Engineering For Elongated Storage-shelf-life
Applications of mRNA Therapeutics
mRNA-based Vaccines Services
mRNA-based Protein Replacement Drug Development
mRNAs For Tissue Regeneration Services
mRNAs For Cancer Immunotherapy Services
Allergy Tolarization With mRNA Therapeutics
mRNAs for Genome Engineering Services
Genetic Reprogramming Of Cells And Tissue With mRNA Services
mRNA-based Cell Therapy Services
mRNA For Infectious Diseases Services
mRNAs for Cancer Vaccine Development
Stable Cell Line Construction Services
Gene Knock-Out Cell Line Construction Service
Overexpressing Cell Line Construction Service
Luciferase Tagging Cell Line Construction Service
GFP Tagging Cell Line Construction Service
Gene Knock-In Stable Cell Line Construction Services
Point Mutation Stable Cell Line Construction Services
Tet Inducible Gene Expression Stable Cell Line Construction Services
SHRNA Gene Knockdown Stable Cell Line Construction
Protein Production Services
BioActive™ Protein Production Services
BioActive™ Receptor Protein Production Services
BioActive™ CD Molecule Protein Production
BioActive™ Immunotherapy Protein Production Services
BioActive™ Secretory Protein Production
BioActive™ Vesicles Proteins Production
BioActive™ Peroxisomes Proteins Production
Bioactive™ Custom Endoplasmic Reticulum Protein Production Service
Bioactivetm Custom Interleukin Production Service
BioActive™ Cancer Protein Production Services
BioActive™ Diagnostic Protein Production Services
BioActive™ Biological Target Protein Production
BioActive™ Biomarker Protein Production Service
BioActive™ Epigenetic Protein Production Services
BioActive™ Enzyme Protein Production Services
BioActive™ Protease Protein Production
BioActiveTM Nuclease Protein Production
BioActive™ Kinase Protein Production
BioActive™ Protease Protein Production Services
Bioactive™ Custom Cell Surface Receptors
BioActive™ Cytokine Production Service
BioActive™ Transcription Factors Production Service
Bioactive™ Fc Receptor Protein Production Services
Bioactive™ Igg-Fc Control Protein Production Services
Bioactive™ Custom Mitochondria Protein Production Service
Bioactive™ Custom Enzymes Production Service
BioActive™ Fluorescence Protein Production Services
Biotesting Services
Chromosome Analysis
High Resolution HLA Typing
Mycoplasma Testing
Endotoxin Testing
Western Blot Services
Co-Immunoprecipitation Service
Dual-Luciferase Reporter (DLR) Assay
RNA Immunoprecipitation Service
Electrophoretic Mobility Shift Assay
Yeast Two-hybrid Service
Affinity Purification And Mass Spectrometry (AP-MS)
Multiplex Immunofluorescence And Multispectral Imaging Service
SDS-PAGE & Silver Staining Service
Protein Identification By SDS-PAGE And LC-MS/MS
Cell Viability And Cytotoxicity Assays
Soft Agar Colony Formation Assay
Annexin V-FITC/PI Apoptosis Assay
Transwell Migration Assay
Cell Cycle Analysis By DNA Content
Real-time Quantitative PCR Services
Enzyme-Linked Immunosorbent Assay (ELISA)
Scanning Electron Microscopy (SEM) Service
Transmission Electron Microscopy Services
Organoid Services
Custom Organoid Culture Service: The Technologies
Submerged Matrigel Culture For Organoid Production
Air–Liquid Interface Culture For Organoid Production
Microfluidic 3D Culture For Organoid Production
Custom Organoid Culture Service
Brain Organoid Culture Service
Lung Organoids Culture Service
Liver Organoids Culture Service
Optic Organoid Culture Service
Inner Ear Organoid Culture Service
Intestine Organoid Culture Service
Oesophageal Organoids Culture Service
Kidney Organoid Culture Service
Breast Organoid Culture Service
Thyroid Organoid Culture Service
Bladder Organoid Culture Service
Oesophageal Organoid Culture Service
Female Reproductive Tract Organoid Culture Service
Gastric Organoid Culture Service
Kidney Organoid Culture Service
Pancreatic Organoid Culture Service
Prostate Organoid Culture Service
Spleen Organoid Culture Service
Applications Of Organoid Culture
Organoids For Disease Modeling
Organoids For Toxicology Testing
Organoids For Regenerative Medicine Research
Organoids For Preclinical Disease Modelling
Organoids For Developmental Biology Research
Drug Screening With Organoids
Organoid Characterization Service
Morphological Analysis Of Organoids
Organoid Counting
Bulk Gene Expression Analysis For Organoids
Organoid Analysis With Flow Cytometry
LNPs for mRNA Delivery
Liposome Production Services
Liposome Production with Thin-Film Hydration
Liposomes Production with Injection Technologies
Liposome Production by Sonication Method
Liposome Production by High-Pressure Extrusion Method
Liposome Production by Reverse-Phase Evaporation Method
Liposome Production by Calcium-Induced Fusion Method
Liposome Production by Dehydration-Rehydration Method
Liposomes Production by Freeze-Thaw Method
Liposomes Production by Microfluidization Method
Liposomes Production by Supercritical Fluids (SCF)
Ferritin-based Protein-nanoparticle Production Service
Exosomes for mRNA Delivery
Liposome Characterization Services
Physical Characterization of Liposomes
Chemical Characterization of Liposomes
Biological Characterization of Liposomes
DNA Barcoding Technology for High Throughput Cell-Nanoparticle Study
Custom Protein Labeling Services
Protein Labeling With Fluorophores
Custom Protein Labeling With Enzymes
Custom Protein Labeling With Oligonucleotides
Custom Protein Labeling With Gold Nanoparticles
Custom Protein Labeling With PEGS
Custom Protein Labeling With Small Molecule Drugs
Custom Protein Labeling With Peptides
Custom Protein Labeling With Agarose
CRISPR/cas9 Therapeutics Development
CRISPR for Genome Editing
Home
Productsindex
Gene
mRNA Productsindex
mRNAs for Cancer Vaccine Researchlists
STn-KLH Circular RNA for Cancer Vaccine Research
CVAC-ORNA-0443
STn-KLH Circular RNA for Cancer Vaccine Research
Source：In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names：STn-KLH plus Detox Vaccine
Specification Sheet
Request a quote
SKU：CVAC-ORNA-0443-LNP
Product Name：STn-KLH Circular RNA-LNP for Cancer Vaccine Research
Product Description：ALG-ORNA-0001 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU：CVAC-ORNA-0443
Product Name：STn-KLH Circular RNA for Cancer Vaccine Research
Product Description：In Vitro Transcribed mRNA template encoding STn-KLH was further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU：CVAC-ORNA-0443-LNP
Product Name：STn-KLH Circular RNA-LNP for Cancer Vaccine Research
Product Description：ALG-ORNA-0001 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU：CVAC-ORNA-0443
Product Name：STn-KLH Circular RNA for Cancer Vaccine Research
Product Description：In Vitro Transcribed mRNA template encoding STn-KLH was further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
5'-UTR:
5' -untranslated region derived from human alpha-globin RNA with an optimized Kozak sequence
ORF:
STn-KLH
3'-UTR:
3' UTR comprising two sequence elements derived from the aminoterminal enhancer of split (AES) mRNA and the mitochondrial encoded 12S ribosomal RNA
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.5
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Cancer Vaccine Research
Background

Gene Alias

STn-KLH plus Detox Vaccine

Background

Description: A vaccine comprised of a synthetic Sialyl-Tn antigen linked to the protein carrier, keyhole limpet hemocyanin (KLH), administered with immunostimulant, Detox. Vaccination with STn-KLH plus Detox may elicit an IgG-based anti-STn antibody response and ultimately a cytotoxic T-cell response against STn-expressing cancer cells. (NCIT_C2501).

RECOMMENDED PRODUCTS
BioActive Human ABL1 (V299L,T315A,F317L,F317V,F317I,F317C) Recombinant Protein,Fc Tag
ABL1

SGRP00624

BioActive Human ABL1 (V299L,T315A,F317L,F317V,F317I,F317C) Recombinant Protein,Fc Tag
View Price and Availability
BioActive Human ABL1 (T315A,F317L,F317V,F317I,F317C,V299L) Recombinant Protein,Fc Tag
ABL1

SGRP00628

BioActive Human ABL1 (T315A,F317L,F317V,F317I,F317C,V299L) Recombinant Protein,Fc Tag
View Price and Availability
BioActive Human AKT1 (Q79K,E17K) Recombinant Protein,Fc Tag
AKT1

SGRP00630

BioActive Human AKT1 (Q79K,E17K) Recombinant Protein,Fc Tag
View Price and Availability
BioActive Human AKT1 (H238Y) Recombinant Protein,Fc Tag
AKT1

SGRP00631

BioActive Human AKT1 (H238Y) Recombinant Protein,Fc Tag
View Price and Availability
BioActive Human ALK (G1123S) Recombinant Protein,Fc Tag
ALK

SGRP00637

BioActive Human ALK (G1123S) Recombinant Protein,Fc Tag
View Price and Availability
Products
BioActive Proteins mRNA Products
Services
Molecular Cloning Services Protein Interaction Testings Virus Production Services Antibody Production Services In Vitro Transcribed mRNA Services Stable Cell Line Construction Services Protein Production Services Biotesting Services Organoid Services LNPs for mRNA Delivery Custom Protein Labeling Services CRISPR/cas9 Therapeutics Development
Company
About Us Contact Us Press Releases
Social Media
Commercial / Technical Support:+1 (425) 247-3088
Email:info@seattle-genova.com    Address:18110 SE 34TH STE 455, Vancouver, WA 98683    Fax:+1 (425) 650-9990
www.seattle-genova.com © 2022 Seattle Genova All Rights Reserved. Privacy Policy
0.128541s