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Varicella-zoster virus DUT ORF8 Protein Circular RNA
VAC-RNA-209
Varicella-zoster virus DUT ORF8 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)
SKU:VAC-RNA-209-LNP
Product Name:Varicella-zoster virus DUT ORF8 Protein Circular RNA-LNP
Product Description:VAC-RNA-209 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-209
Product Name:Varicella-zoster virus DUT ORF8 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus DUT ORF8 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-209-LNP
Product Name:Varicella-zoster virus DUT ORF8 Protein Circular RNA-LNP
Product Description:VAC-RNA-209 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-209
Product Name:Varicella-zoster virus DUT ORF8 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus DUT ORF8 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A210
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.212
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P09254

Gene Alias

Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)

Background

FUNCTION: Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA. {ECO:0000255|HAMAP-Rule:MF_04031}.

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