Applications
Products
Service
Company
Gene Accession
P09308
Gene Alias
Envelope glycoprotein L (gL)
Background
FUNCTION: The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. {ECO:0000255|HAMAP-Rule:MF_04034}.
