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Varicella-zoster virus ORF16 Protein Circular RNA
VAC-RNA-215
Varicella-zoster virus ORF16 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) (PAP)
SKU:VAC-RNA-215-LNP
Product Name:Varicella-zoster virus ORF16 Protein Circular RNA-LNP
Product Description:VAC-RNA-215 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-215
Product Name:Varicella-zoster virus ORF16 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF16 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-215-LNP
Product Name:Varicella-zoster virus ORF16 Protein Circular RNA-LNP
Product Description:VAC-RNA-215 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-215
Product Name:Varicella-zoster virus ORF16 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF16 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A216
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.218
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P09274

Gene Alias

DNA polymerase processivity factor (DNA-binding gene 16 protein) (Polymerase accessory protein) (PAP)

Background

FUNCTION: Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit. Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA. Facilitates the origin-binding protein loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity). {ECO:0000250}.

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