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Varicella-zoster virus ORF35 Protein Circular RNA
VAC-RNA-224
Varicella-zoster virus ORF35 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Protein UL24 homolog
SKU:VAC-RNA-224-LNP
Product Name:Varicella-zoster virus ORF35 Protein Circular RNA-LNP
Product Description:VAC-RNA-224 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-224
Product Name:Varicella-zoster virus ORF35 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF35 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-224-LNP
Product Name:Varicella-zoster virus ORF35 Protein Circular RNA-LNP
Product Description:VAC-RNA-224 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-224
Product Name:Varicella-zoster virus ORF35 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF35 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A225
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.227
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P09288

Gene Alias

Protein UL24 homolog

Background

FUNCTION: May participate in nuclear egress of viral particles. Plays a role in the dispersal of several host nucleolar proteins including NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively impact on nuclear egress, UL24 supposedly acts on this process through its effect on host nucleoli (By similarity). {ECO:0000250}.

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