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Varicella-zoster virus ORF51 Protein Circular RNA
VAC-RNA-203
Varicella-zoster virus ORF51 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Replication origin-binding protein (OBP) (OriBP)
SKU:VAC-RNA-203-LNP
Product Name:Varicella-zoster virus ORF51 Protein Circular RNA-LNP
Product Description:VAC-RNA-203 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-203
Product Name:Varicella-zoster virus ORF51 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF51 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-203-LNP
Product Name:Varicella-zoster virus ORF51 Protein Circular RNA-LNP
Product Description:VAC-RNA-203 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-203
Product Name:Varicella-zoster virus ORF51 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF51 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A204
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.206
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P09299

Gene Alias

Replication origin-binding protein (OBP) (OriBP)

Background

FUNCTION: Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins. In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication (By similarity). {ECO:0000250}.

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