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Gene Accession
P09300
Gene Alias
DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
Background
FUNCTION: Component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs. The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase. {ECO:0000255|HAMAP-Rule:MF_04010}.
