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Varicella-zoster virus ORF59 Protein Circular RNA
VAC-RNA-235
Varicella-zoster virus ORF59 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)
SKU:VAC-RNA-235-LNP
Product Name:Varicella-zoster virus ORF59 Protein Circular RNA-LNP
Product Description:VAC-RNA-235 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-235
Product Name:Varicella-zoster virus ORF59 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF59 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-235-LNP
Product Name:Varicella-zoster virus ORF59 Protein Circular RNA-LNP
Product Description:VAC-RNA-235 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-235
Product Name:Varicella-zoster virus ORF59 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF59 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A236
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.238
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P09307

Gene Alias

Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) (UNG)

Background

FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes. {ECO:0000255|HAMAP-Rule:MF_04046}.

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