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Varicella-zoster virus ORF6 Protein Circular RNA
VAC-RNA-212
Varicella-zoster virus ORF6 Protein Circular RNA
Source:In vitro transcribed mRNA was further circularized to make this product as a circular RNA.
Alternative Names:DNA primase (EC 2.7.7.-)
SKU:VAC-RNA-212-LNP
Product Name:Varicella-zoster virus ORF6 Protein Circular RNA-LNP
Product Description:VAC-RNA-212 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-212
Product Name:Varicella-zoster virus ORF6 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF6 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
SKU:VAC-RNA-212-LNP
Product Name:Varicella-zoster virus ORF6 Protein Circular RNA-LNP
Product Description:VAC-RNA-212 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
SKU:VAC-RNA-212
Product Name:Varicella-zoster virus ORF6 Protein Circular RNA
Product Description:In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF6 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
PROPERTIES
ORF:
=A213
Modifications:
N1-methyl-pseudouridine
Neutral Lipid:
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)
Cholesterol:
Cholesterol
Lonizable Lipid:
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 (PEG2000-DMG)
PEG-lipid:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)− 8-oxooctyl)amino)octanoate)(SM-102)
Storage:
-80 °C
Buffer:
PBS, pH7.215
Cryoprotectant:
Trehalose
Related Categories
mRNAs for Vaccine Development
Background

Gene Accession

P09270

Gene Alias

DNA primase (EC 2.7.7.-)

Background

FUNCTION: Essential component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs. {ECO:0000255|HAMAP-Rule:MF_04011}.

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