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mRNAs for Vaccine Development
mRNAs for Vaccine Development

mRNAs for Vaccine Development

mRNA vaccines have been authorized for emergency use much less than one year after the emergence of COVID-19, demonstrating the extremely good improvement pace of the mRNA platform technology. However, even as the versatility of the mRNA platform could permit for the global development of latest vaccines, constraints which includes restrained intellectual property (IP), excessive price of goods, raw material bottlenecks, and shortage of skilled workforce restriction access to mRNA vaccines in low- and middle-earnings countries. Here, Seattle Genova presents a perspective on the global state of mRNA vaccine development for infectious diseases, and the manufacturing capabilities needed to enable vaccine access to fight ongoing/future pandemic and epidemic threats.

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Gene Name
Product Name
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Envelope protein E
DENV-2 (isolate Malaysia M2) Envelope protein E Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-072
DENV-2 (isolate Malaysia M2) Envelope protein E Protein Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (isolate Malaysia M2) Envelope protein E Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-072-LNP
DENV-2 (isolate Malaysia M2) Envelope protein E Protein Circular RNA-LNP
VAC-RNA-072 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Small envelope protein M (Matrix protein)
DENV-2 (strain Thailand/TH-36/1958) Small envelope protein M (Matrix protein) Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-073
DENV-2 (strain Thailand/TH-36/1958) Small envelope protein M (Matrix protein) Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (strain Thailand/TH-36/1958) Small envelope protein M (Matrix protein) Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-073-LNP
DENV-2 (strain Thailand/TH-36/1958) Small envelope protein M (Matrix protein) Circular RNA-LNP
VAC-RNA-073 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
Envelope protein E
DENV-2 (isolate Malaysia M3) Envelope protein E Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-074
DENV-2 (isolate Malaysia M3) Envelope protein E Protein Circular RNA
In Vitro Transcribed mRNA template encoding DENV-2 (isolate Malaysia M3) Envelope protein E Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-074-LNP
DENV-2 (isolate Malaysia M3) Envelope protein E Protein Circular RNA-LNP
VAC-RNA-074 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
GP
ZEBOV(strain Gabon-94) GP Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-075
ZEBOV(strain Gabon-94) GP Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Gabon-94) GP Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-075-LNP
ZEBOV(strain Gabon-94) GP Protein Circular RNA-LNP
VAC-RNA-075 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
NP
ZEBOV(strain Mayinga-76) NP Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-076
ZEBOV(strain Mayinga-76) NP Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Mayinga-76) NP Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-076-LNP
ZEBOV(strain Mayinga-76) NP Protein Circular RNA-LNP
VAC-RNA-076 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
GP
ZEBOV(strain Mayinga-76) GP Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-077
ZEBOV(strain Mayinga-76) GP Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Mayinga-76) GP Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-077-LNP
ZEBOV(strain Mayinga-76) GP Protein Circular RNA-LNP
VAC-RNA-077 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
GP
ZEBOV(strain Kikwit-95) GP Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-078
ZEBOV(strain Kikwit-95) GP Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Kikwit-95) GP Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-078-LNP
ZEBOV(strain Kikwit-95) GP Protein Circular RNA-LNP
VAC-RNA-078 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
GP
ZEBOV(strain Eckron-76) GP Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-079
ZEBOV(strain Eckron-76) GP Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Eckron-76) GP Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-079-LNP
ZEBOV(strain Eckron-76) GP Protein Circular RNA-LNP
VAC-RNA-079 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
VP35
ZEBOV(strain Mayinga-76) VP35 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-080
ZEBOV(strain Mayinga-76) VP35 Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Mayinga-76) VP35 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-080-LNP
ZEBOV(strain Mayinga-76) VP35 Protein Circular RNA-LNP
VAC-RNA-080 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
VP40
ZEBOV(strain Mayinga-76) VP40 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-081
ZEBOV(strain Mayinga-76) VP40 Protein Circular RNA
In Vitro Transcribed mRNA template encoding ZEBOV(strain Mayinga-76) VP40 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-081-LNP
ZEBOV(strain Mayinga-76) VP40 Protein Circular RNA-LNP
VAC-RNA-081 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
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