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mRNAs for Vaccine Development
mRNAs for Vaccine Development

mRNAs for Vaccine Development

mRNA vaccines have been authorized for emergency use much less than one year after the emergence of COVID-19, demonstrating the extremely good improvement pace of the mRNA platform technology. However, even as the versatility of the mRNA platform could permit for the global development of latest vaccines, constraints which includes restrained intellectual property (IP), excessive price of goods, raw material bottlenecks, and shortage of skilled workforce restriction access to mRNA vaccines in low- and middle-earnings countries. Here, Seattle Genova presents a perspective on the global state of mRNA vaccine development for infectious diseases, and the manufacturing capabilities needed to enable vaccine access to fight ongoing/future pandemic and epidemic threats.

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Gene Name
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gL ORF60
Varicella-zoster virus gL ORF60 Protein Circular RNA
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Product Description
VAC-RNA-592
Varicella-zoster virus gL ORF60 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus gL ORF60 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-592-LNP
Varicella-zoster virus gL ORF60 Protein Circular RNA-LNP
VAC-RNA-592 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
HELI ORF55
Varicella-zoster virus HELI ORF55 Protein Circular RNA
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Product_name
Product Description
VAC-RNA-593
Varicella-zoster virus HELI ORF55 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus HELI ORF55 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-593-LNP
Varicella-zoster virus HELI ORF55 Protein Circular RNA-LNP
VAC-RNA-593 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF48
Varicella-zoster virus ORF48 Protein Circular RNA
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Product_name
Product Description
VAC-RNA-594
Varicella-zoster virus ORF48 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF48 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-594-LNP
Varicella-zoster virus ORF48 Protein Circular RNA-LNP
VAC-RNA-594 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF46
Varicella-zoster virus ORF46 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-595
Varicella-zoster virus ORF46 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF46 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-595-LNP
Varicella-zoster virus ORF46 Protein Circular RNA-LNP
VAC-RNA-595 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF38
Varicella-zoster virus ORF38 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-596
Varicella-zoster virus ORF38 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF38 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-596-LNP
Varicella-zoster virus ORF38 Protein Circular RNA-LNP
VAC-RNA-596 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF35
Varicella-zoster virus ORF35 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-597
Varicella-zoster virus ORF35 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF35 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-597-LNP
Varicella-zoster virus ORF35 Protein Circular RNA-LNP
VAC-RNA-597 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF32
Varicella-zoster virus ORF32 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-598
Varicella-zoster virus ORF32 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF32 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-598-LNP
Varicella-zoster virus ORF32 Protein Circular RNA-LNP
VAC-RNA-598 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF16
Varicella-zoster virus ORF16 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-599
Varicella-zoster virus ORF16 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF16 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-599-LNP
Varicella-zoster virus ORF16 Protein Circular RNA-LNP
VAC-RNA-599 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
ORF15
Varicella-zoster virus ORF15 Protein Circular RNA
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SKU
Product_name
Product Description
VAC-RNA-600
Varicella-zoster virus ORF15 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus ORF15 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-600-LNP
Varicella-zoster virus ORF15 Protein Circular RNA-LNP
VAC-RNA-600 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
DUT ORF8
Varicella-zoster virus DUT ORF8 Protein Circular RNA
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Product_name
Product Description
VAC-RNA-601
Varicella-zoster virus DUT ORF8 Protein Circular RNA
In Vitro Transcribed mRNA template encoding Varicella-zoster virus DUT ORF8 Protein Circular RNAwas further circularized with Seattle Genova's OSTAR technology. The resulting circRNAs are very stable and have low immunogenicity enabling prolonged protein translation in different cells without cellular toxicity.
VAC-RNA-601-LNP
Varicella-zoster virus DUT ORF8 Protein Circular RNA-LNP
VAC-RNA-601 was encapsulated with lipid nanoparticles through Seattle Genova's LipoX platform.
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